Abdominal Obesity and Health Risks

By Agencia de Investigación y Desarrollo

Research from the National Institute of Respiratory Diseases (INER) shows that besides smoking, other factors associated with the development of lung cancer are the smoke from burning lumber and coal, as well as pollutant particles.

“It has been shown that the upturn in cases of lung cancer is possibly related to these particles,” explains Patricia Gorocica from the INER, who, alongside her research team, has been working on an alternative therapy to boost the immune system of patients with this disease.

The specialist adds that for several years it has been known that the immune system has all the mechanisms to watch and destroy tumor cells as they develop, but sometimes these mechanisms are not effective for reasons related to the tumor or alterations of the patient’s organism.

Based on this principle, research at INER is focused on regulating the immune system against tumors. The tumors that can be more easily eliminated are the ones that express specific antigens.

Patricia Gorocica, chief of the Department of Biochemical Research at INER, says that with current technology it is possible to manipulate the immune response against tumors. “We are developing at the lab a system of cell activation from the patient’s own blood so it can eliminate its tumors,” she said.

This is a new research, but it could be consolidated as an alternative therapy for patients with lung cancer. The work is being done with the support of the institutes of Biotechnology and Chemistry of the Autonomous National University of Mexico (UNAM), hoping that others will add to the cause, since this research requires a multi-disciplinary team in order for success.

Gorocica adds that manipulating the immune system could be a new complementary therapy to chemo and radiotherapy usually used for treating lung cancer.

The research at INER is mainly focused in patients with lung adenocarcinoma, a type of cancer that has the most alterations in its tumor cells. It affects people of various ages, particularly people over 40, but has been known to affect younger people as well.


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